Article
Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA.
Genome research - 1 Nov 2001
Sano Y, Shimada T, Nakashima H, Nicholson R H, Eliason J F, Kocarek T A, Ko M S
Abstract excerpt
Mammals achieve gene dosage control by (1) random X-chromosome inactivation in females, (2) parental origin-specific imprinting of selected autosomal genes, and (3) random autosomal inactivation. Genes belonging to the third category of epigenetic phenomenon are just now emerging, with only six identified so far. Here we report three additional genes, Nubp2, Igfals, and Jsap1, that show 50%-methylated CpG sites...
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