Article
A non-MHC locus essential for autoimmune type I diabetes in the Komeda Diabetes-Prone rat.
The Journal of clinical investigation - 15 Oct 1997
Yokoi N, Kanazawa M, Kitada K, Tanaka A, Kanazawa Y, Suda S, Ito H, Serikawa T, Komeda K
Abstract excerpt
The Long-Evans Tokushima Lean (LETL) rat, characterized by rapid onset of insulin-dependent (type I) diabetes mellitus (IDDM), no sex difference in the incidence of IDDM, autoimmune destruction of pancreatic beta cells, and no significant T cell lymphopenia, is a desirable animal model for human...
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