Article
Identification of a major gene responsible for type 1 diabetes in the Komeda diabetes-prone rat.
Experimental animals - 1 Apr 2005
Yokoi Norihide
Abstract excerpt
Type 1 diabetes mellitus is an autoimmune disease involving both environmental and genetic factors. Genetic analyses in humans and rodents have shown that the major histocompatibility complex (MHC) is a major genetic factor and that several other genes may be involved in the development of the disease. We performed genetic analysis of type 1 diabetes in a newly established animal model, the Komeda diabetes-prone...
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