Article
Iddm30 controls pancreatic expression of Ccl11 (Eotaxin) and the Th1/Th2 balance within the insulitic lesions.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2014
Chao Gary Y C, Wallis Robert H, Marandi Leili, Ning Terri, Sarmiento Janice, Paterson Andrew D, Poussier Philippe
Abstract excerpt
The autoimmune diabetic syndrome of the BioBreeding diabetes-prone (BBDP) rat is a polygenic disease that resembles in many aspects human type 1 diabetes (T1D). A successful approach to gain insight into the mechanisms underlying genetic associations in autoimmune diseases has been to identify and map disease-related subphenotypes that are under simpler genetic control than the full-blown disease. In this study,...
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