Article
Bactericidal action of lysozymes attached with various sizes of hydrophobic peptides to the C-terminal using genetic modification.
FEBS letters - 22 Sept 1997
Arima H, Ibrahim H R, Kinoshita T, Kato A
Abstract excerpt
The genetic modification of lysozyme was attempted to improve the bactericidal activity against Gram-negative bacteria E. coli. The different lengths of hydrophobic peptides were attached to the C-terminus of the hen egg white lysozyme to investigate the most effective length of the hydrophobic peptides for killing bacteria. The oligonucleotides encoding Phe-Val-Pro (H3), Phe-Phe-Val-Ala-Pro (H5) and...
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