Article
Structural requirements of signal peptide in insect cell.
Nucleic acids symposium series (2004) - 1 Jan 2004
Tsuchiya Yoshinori, Morioka Kazuki, Shirai Jyunsuke, Yoshida Kazuo
Abstract excerpt
In order to increase the proteinic secretion quantity of production in insect cell, the N-terminal and the hydrophobic core region of the chicken lysozyme signal peptide (CLSP) was altered. A hybrid gene composed of CLSP gene and human lysozyme (HLY) gene from short DNA oligomers was used for the production of recombinant HLY in insect cell using vacuole virus expression system. In contrast with the results in...
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