Article
Inhibition of growth of human leukemia cell lines by retrovirally expressed wild-type p16INK4A.
Leukemia - 1 Oct 1997
Gombart A F, Yang R, Campbell M J, Berman J D, Koeffler H P
Abstract excerpt
Loss of the p16INK4A gene by homozygous deletions or point mutations is attributed to the development of many types of cancers including leukemia. T cell acute lymphoblastic leukemias (T-ALLs) and B-cell ALLs show a remarkable rate of 75 and 20% homozygous deletion of this gene, respectively. Res...
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