Article
Detection of two new polymorphic sites in the human interleukin-1 beta gene: lack of association with schizophrenia in a French population.
Psychiatric genetics - 1 Jan 1997
Laurent C, Thibaut F, Ravassard P, Campion D, Samolyk D, Lafargue C, Petit M, Martinez M, Mallet J
Abstract excerpt
The pathogenesis of schizophrenia might involve abnormal development of the human brain. Interleukin-1 beta is a cytokine implicated in the development of the central nervous system and therefore its gene is a candidate gene in schizophrenia. Polymorphisms within the coding sequence and the 3'UTR...
Topics
- Adult
- Alleles
- Amino Acid Substitution
- Asparagine
- Aspartic Acid
- Exons
- Female
- France
- Gene Frequency
- Genotype
- Humans
- Interleukin-1
- Male
- Middle Aged
- Point Mutation
- Polymerase Chain Reaction