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An Association Between Functional Polymorphisms of the Interleukin 1 Gene Complex and Schizophrenia Using Transmission Disequilibrium Test.

Archivum immunologiae et therapiae experimentalis - 1 Dec 2016

Kapelski Pawel, Skibinska Maria, Maciukiewicz Malgorzata, Pawlak Joanna, Dmitrzak-Weglarz Monika, Szczepankiewicz Aleksandra, Zaremba Dorota, Twarowska-Hauser Joanna

Abstract excerpt

IL1 gene complex has been implicated in the etiology of schizophrenia. To assess whether IL1 gene complex is associated with susceptibility to schizophrenia in Polish population we conducted family-based study. Functional polymorphisms from IL1A (rs1800587, rs17561, rs11677416), IL1B (rs1143634, rs1143643, , , , , ) and IL1RN (, , , ) genes...

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Topics

Adult
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Interleukin 1 Receptor Antagonist Protein
Interleukin-1beta
Linkage Disequilibrium
Male
Poland
Polymorphism, Single Nucleotide
Schizophrenia
Young Adult

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PMID: 28083609
DOI: 10.1007/s00005-016-0434-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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