Article
Interleukin-1 gene complex in schizophrenia: an association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2006
Saiz Pilar A, Garcia-Portilla Maria P, Arango Celso, Morales Blanca, Martinez-Barrondo Sara, Alvarez Victoria, Coto Eliecer, Fernandez Juan, Bousono Manuel, Bobes Julio
Abstract excerpt
The aim of this study is to investigate the association between three polymorphisms of the interleukin-1 (IL-1) gene complex and schizophrenia. We genotyped 228 outpatients with schizophrenia (DSM-IV criteria) and 419 unrelated healthy controls. The following polymorphisms were analyzed: IL-1alpha -889 C/T, IL-1beta +3953 C/T, and IL-1RA (86 bp)n. No significant differences in genotype or in allelic distribution...
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