Article
Partial resistance to gD-mediated interference conferred by mutations affecting herpes simplex virus type 1 gC and gK.
Journal of virology - 1 Oct 1997
Pertel P E, Spear P G
Abstract excerpt
Cells expressing herpes simplex virus (HSV) gD can be resistant to HSV entry as a result of gD-mediated interference. HSV strains differ in sensitivity to this interference, which blocks viral penetration but not binding. Previous studies have shown that mutations or variations in virion-associated gD can confer resistance to gD-mediated interference. Here we show that HSV-1 mutants selected for enhanced ability...
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