Partial resistance to gD-mediated interference conferred by mutations affecting herpes simplex virus type 1 gC and gK.

doi:10.1128/JVI.71.10.8024-8028.1997

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Article

Partial resistance to gD-mediated interference conferred by mutations affecting herpes simplex virus type 1 gC and gK.

Journal of virology - 1 Oct 1997

Pertel P E, Spear P G

Abstract excerpt

Cells expressing herpes simplex virus (HSV) gD can be resistant to HSV entry as a result of gD-mediated interference. HSV strains differ in sensitivity to this interference, which blocks viral penetration but not binding. Previous studies have shown that mutations or variations in virion-associat...

Topics

Animals
CHO Cells
Cricetinae
Genetic Variation
Heparin
Herpesvirus 1, Human
Humans
Mutagenesis
Mutagenesis, Site-Directed
Polymerase Chain Reaction
Tumor Cells, Cultured
Viral Envelope Proteins
Viral Proteins
Virion

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