Article
An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ.
The Journal of general virology - 1 Jun 1994
Balan P, Davis-Poynter N, Bell S, Atkinson H, Browne H, Minson T
Abstract excerpt
Mutants of herpes simplex virus type 1 (HSV-1) lacking glycoproteins gG, gE, gI or the putative gJ were constructed by inserting a lacZ expression cassette within the US4, US8, US7 and US5 genes respectively. Revertant viruses were then constructed by rescue with a wild-type DNA fragment. Each of...
Topics
- Animals
- Antibodies, Viral
- Antigens, Viral
- Base Sequence
- Cell Line
- Cricetinae
- DNA Primers
- Genes, Viral
- Herpesvirus 1, Human
- Humans
- Membrane Fusion
- Membrane Glycoproteins
- Molecular Sequence Data
- Phenotype
- Receptors, Virus
- Viral Envelope Proteins
- Viral Structural Proteins