Article
Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus.
Journal of virology - 1 Dec 1990
Campadelli-Fiume G, Qi S, Avitabile E, Foà-Tomasi L, Brandimarti R, Roizman B
Abstract excerpt
Earlier studies have shown that herpes simplex viruses adsorb to but do not penetrate permissive baby hamster kidney clonal cell lines designated the BJ series and constitutively expressing the herpes simplex virus 1 (HSV-1) glycoprotein D (gD). To investigate the mechanism of the restriction, th...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Line
- DNA, Viral
- Genes, Viral
- Mutation
- Phenotype
- Restriction Mapping
- Simplexvirus
- Transfection
- Viral Envelope Proteins
- Viral Plaque Assay