Article
A highly specific functional test for factor V leiden: A modified tissue factor assay for activated protein C resistance.
Haemostasis - 1 Jan 2000
Arkel Y S, Ku D, Kamiyama M, Pajaro R, Alder H, Marchand A
Abstract excerpt
We compared the sensitivity and specificity of a tissue factor-based assay (FVR) with the addition of a phospholipid/silica preparation, to the commercially available aPTT-based method, APCR (CoatestTM), and a modified aPTT-based method (APCM) which utilized factor V-depleted plasma, for the dete...
Topics
- Activated Protein C Resistance
- Antibodies, Anticardiolipin
- Antiphospholipid Syndrome
- Blood Coagulation Tests
- Factor V
- Humans
- Indicators and Reagents
- Kaolin
- Lupus Coagulation Inhibitor
- Mutation
- Partial Thromboplastin Time
- Phospholipids
- Polymerase Chain Reaction
- Reference Values
- Sensitivity and Specificity
- Silicon Dioxide
- Thromboplastin