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Article

A highly specific functional test for factor V leiden: A modified tissue factor assay for activated protein C resistance.

Haemostasis - 1 Jan 2000

Arkel Y S, Ku D, Kamiyama M, Pajaro R, Alder H, Marchand A

Abstract excerpt

We compared the sensitivity and specificity of a tissue factor-based assay (FVR) with the addition of a phospholipid/silica preparation, to the commercially available aPTT-based method, APCR (CoatestTM), and a modified aPTT-based method (APCM) which utilized factor V-depleted plasma, for the detection of the factor V Leiden mutation. A total of 110 patients were included in this study. This included 32 patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9731110
DOI: 10.1159/000217470

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A highly specific functional test for factor V leiden: A modified tissue factor assay for activated protein C resistance.PMID 9731110Read ↗

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