Evaluation of original and modified APC-resistance tests in unselected outpatients with clinically suspected thrombosis and in healthy controls.

Article

Evaluation of original and modified APC-resistance tests in unselected outpatients with clinically suspected thrombosis and in healthy controls.

Thrombosis and haemostasis - 1 Feb 1997

Svensson P J, Zöller B, Dahlbäck B

Abstract excerpt

APC-resistance is the most common hereditary condition associated with venous thrombosis. It is in a majority of cases due to a single point mutation in the factor V gene (FVR506Q). Currently used functional APC-resistance tests have 85-90% sensitivity and specificity for the FVR506Q mutation. A...

Topics

Adult
Aged
Aged, 80 and over
Blood Coagulation Tests
Factor V
Female
Genotype
Humans
Male
Middle Aged
Outpatients
Protein C
Sensitivity and Specificity
Thrombophlebitis
Thrombosis

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