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Article

Molecular basis for different pore properties of potassium channels from the rat brain Kv1 gene family.

Pflugers Archiv : European journal of physiology - 1 Nov 1997

Gòmez-Hernandez J M, Lorra C, Pardo L A, Stühmer W, Pongs O, Heinemann S H, Elliott A A

Abstract excerpt

Members of the rat brain Kv1 family of cloned potassium channels are structurally highly homologous, but have diverse conductance and pharmacological characteristics. Here we present data on the effects of mutating residues K533 in the P-region and H471 in the S4-S5 linker of Kv1.4 to their equiv...

Topics

Animals
Brain
Electric Conductivity
Female
Magnesium
Molecular Biology
Multigene Family
Mutation
Potassium Channels
Rats
Tetraethylammonium
Xenopus laevis

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Identifiers

PMID: 9305996
DOI: 10.1007/s004240050449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9305996-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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