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Article

Comparison of H5, S6, and H5-S6 exchanges on pore properties of voltage-dependent K+ channels.

The Journal of biological chemistry - 13 May 1994

Taglialatela M, Champagne M S, Drewe J A, Brown A M

Abstract excerpt

Evidence is now substantial that membrane segments besides H5 contribute to the pore of K+ channels. We found that substitution of the H5 region of Shaker B (ShB) with the corresponding sequence of NGK2 expressed channels which retained the single channel K+ conductance (gK+) of the host ShB channel. A reverse chimera with ShB H5 region transplanted into NGK2 also retained the gK+ of the host NGK2. Point...

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PMID: 8188663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Comparison of H5, S6, and H5-S6 exchanges on pore properties of voltage-dependent K+ channels.PMID 8188663Read ↗

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