Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maintenance of an unusual polypurine tract in HIV-2: stability to passage in culture.

Virology - 15 Sept 1997

Lauermann V, Hughes S H, Peden K W

Abstract excerpt

A stretch of purine residues, the polypurine tract (PPT), is found in all retroviruses and is used to initiate plus-strand DNA synthesis. While the PPT of most lentiviruses is a homogeneous sequence of purine residues, the PPT of some isolates of the human and simian immunodeficiency viruses is interrupted with a single pyrimidine residue. The ROD strain of human immunodeficiency virus type 2 (HIV-2) has such a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Consensus Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to DNA, Viral

Share to Genetic Variation

Share to Models, Genetic

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 9299633
DOI: 10.1006/viro.1997.8721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Maintenance of an unusual polypurine tract in HIV-2: stability to passage in culture.PMID 9299633Read ↗

Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity.Semantic proximity Read ↗

Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication.Semantic proximity Read ↗

Mutations in the central polypurine tract of HIV-1 result in delayed replication.Semantic proximity Read ↗

A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication.Semantic proximity Read ↗

Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.Semantic proximity Read ↗

Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.Semantic proximity Read ↗

SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness.Semantic proximity Read ↗

Reversion of a polymerase-defective integrated HIV-1 genome.Semantic proximity Read ↗

The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retrovirusesSemantic proximity Read ↗

In vitro analysis of the effects of mutations in the G-tract of the human immunodeficiency virus type 1 polypurine tract on RNase H cleavage specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.