Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The repair of DNA methylation damage in Saccharomyces cerevisiae.

Current genetics - 1 Dec 1996

Xiao W, Chow B L, Rathgeber L

Abstract excerpt

The major genotoxicity of methyl methanesulfonate (MMS) is due to the production of a lethal 3-methyladenine (3MeA) lesion. An alkylation-specific base-excision repair pathway in yeast is initiated by a Mag1 3MeA DNA glycosylase that removes the damaged base, followed by an Apn1 apurinic/ apyrimidinic endonuclease that cleaves the DNA strand at the abasic site for subsequent repair. MMS is also regarded as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to DNA, Fungal
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Mutation

Share to Recombination, Genetic

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 8939806
DOI: 10.1007/s002940050157

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The repair of DNA methylation damage in Saccharomyces cerevisiae.PMID 8939806Read ↗

Interplay of DNA repair pathways controls methylation damage toxicity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast.Semantic proximity Read ↗

Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae.Semantic proximity Read ↗

DNA damage checkpoints are involved in postreplication repair.Semantic proximity Read ↗

MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae.Semantic proximity Read ↗

The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent.Semantic proximity Read ↗

Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.Semantic proximity Read ↗

Involvement of SGS1 in DNA damage-induced heteroallelic recombination that requires RAD52 in Saccharomyces cerevisiae.Semantic proximity Read ↗

In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells.Semantic proximity Read ↗

Evidence for abasic site sugar phosphate-mediated cytotoxicity in alkylating agent treated Saccharomyces cerevisiae.Semantic proximity Read ↗

Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae DNA repair processes: an update.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.