The repair of DNA methylation damage in Saccharomyces cerevisiae.

doi:10.1007/s002940050157

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Article

The repair of DNA methylation damage in Saccharomyces cerevisiae.

Current genetics - 1 Dec 1996

Xiao W, Chow B L, Rathgeber L

Abstract excerpt

The major genotoxicity of methyl methanesulfonate (MMS) is due to the production of a lethal 3-methyladenine (3MeA) lesion. An alkylation-specific base-excision repair pathway in yeast is initiated by a Mag1 3MeA DNA glycosylase that removes the damaged base, followed by an Apn1 apurinic/ apyrimi...

Topics

Adenosine Triphosphatases
Alkylation
DNA Glycosylases
DNA Helicases
DNA Methylation
DNA Repair
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
Ligases
Methyl Methanesulfonate
Mutation
N-Glycosyl Hydrolases
Rad52 DNA Repair and Recombination Protein
Recombination, Genetic
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 8939806
DOI: 10.1007/s002940050157

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8939806-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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