Correlation of p53 protein expression with gene mutation in gall-bladder carcinomas.

doi:10.1111/j.1440-1827.1997.tb04535.x

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Article

Correlation of p53 protein expression with gene mutation in gall-bladder carcinomas.

Pathology international - 1 Aug 1997

Itoi T, Watanabe H, Yoshida M, Ajioka Y, Nishikura K, Saito T

Abstract excerpt

The correlation of p53 protein expression and p53 mutation of 33 gall-bladder carcinomas was studied according to the depth of invasion and grade of cytological atypia. Overexpression of p53 protein was detected by immunostaining in seven (70.0%) of 10 intramucosal and in 16 (69.6%) of 23 invasiv...

Topics

Adenocarcinoma
DNA Primers
Gallbladder Neoplasms
Genes, p53
Humans
Mutation
Neoplasm Proteins
Polymerase Chain Reaction
Polymorphism, Genetic
Tumor Suppressor Protein p53

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