Article
Correlation of p53 protein expression with gene mutation in gall-bladder carcinomas.
Pathology international - 1 Aug 1997
Itoi T, Watanabe H, Yoshida M, Ajioka Y, Nishikura K, Saito T
Abstract excerpt
The correlation of p53 protein expression and p53 mutation of 33 gall-bladder carcinomas was studied according to the depth of invasion and grade of cytological atypia. Overexpression of p53 protein was detected by immunostaining in seven (70.0%) of 10 intramucosal and in 16 (69.6%) of 23 invasive carcinomas. p53 mutation was detected in five (71.4%) of the seven intramucosal carcinomas with overexpression and in...
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