Article
Quantitative study on the correlation between p53 gene mutation and its expression in endometrial carcinoma cell lines.
European journal of gynaecological oncology - 1 Jan 2004
Kamata Y, Watanabe J, Hata H, Hamano M, Kuramoto H
Abstract excerpt
Mutant p53 protein is not degradated but accumulates in the nuclei. However, the relation between p53 gene mutation and quantity of p53 protein has not been clarified yet in endometrial carcinoma. We investigated the correlation between p53 gene mutation and its protein expression quantitatively using 11 cell lines of endometrial adenocarcinoma, endometrioid type and two serous-type cell lines. To examine p53...
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