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Article

Correlation of TP53 mutations and p53 expression in ovarian tumors.

Cancer genetics and cytogenetics - 1 Sept 1998

DiCioccio R A, Werness B A, Peng R, Allen H J, Piver M S

Abstract excerpt

To characterize the involvement of the TP53 tumor suppressor gene in ovarian cancer, mutation analysis of exons 2-11 of TP53 and immunodetection of its protein product, p53, were done in 48 ovarian tumors. Normally, p53 is not immunodetectable. Missense TP53 mutations have been reported to result in p53 accumulation and detection, but mutations generating premature stop codons have not. Mutations were identified...

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Share to Gene Expression Regulation, Neoplastic
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 9723023
DOI: 10.1016/s0165-4608(98)00011-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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