Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat.

doi:10.1161/01.cir.96.4.1078

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Article

Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat.

Circulation - 19 Aug 1997

Kreutz R, Struk B, Stock P, Hübner N, Ganten D, Lindpaintner K

Abstract excerpt

BACKGROUND: We investigated whether an accelerated heart rate (HR), observed in the stroke-prone spontaneously hypertensive rat (SHRSP(HD)), is a primary, genetically determined trait and whether it contributes to blood pressure (BP) regulation in this model of polygenic hypertension. METHODS AND...

Topics

Analysis of Variance
Animals
Blood Pressure
Chromosome Mapping
Female
Genetic Linkage
Genotype
Heart Rate
Hypertension
Male
Rats
Rats, Inbred SHR
Rats, Inbred WKY

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