Article
Genetic analysis of complex cardiovascular traits in the spontaneously hypertensive rat.
Experimental physiology - 1 May 2005
Pravenec Michal, Kren Vladimír
Abstract excerpt
Identification of the genetic determinants of common diseases is a major challenge for current biomedical research. Combining linkage analyses of essentially monogenic cis-regulated expression phenotypes with oligogenic intermediate physiological phenotypes represents a promising approach for identification of quantitative trait loci at the molecular level. In the present review, a genetic analysis of...
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