Article
Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
Molecular pharmacology - 1 Sept 1997
Mäkelä R, Uusi-Oukari M, Homanics G E, Quinlan J J, Firestone L L, Wisden W, Korpi E R
Abstract excerpt
The vast molecular heterogeneity of brain gamma-aminobutyric acid type A (GABAA) receptors forms the basis for receptor subtyping. Using autoradiographic techniques, we established the characteristics of cerebellar granule cell GABAA receptors by comparing wild-type mice with those with a targete...
Topics
- Animals
- Azides
- Benzodiazepines
- Binding Sites
- Bridged Bicyclo Compounds, Heterocyclic
- Carbolines
- Cerebellum
- Convulsants
- Diazepam
- Diuretics
- Furosemide
- GABA Agonists
- GABA Antagonists
- GABA Modulators
- Mice
- Mice, Inbred C57BL
- Mutation
- Pregnanolone