Article
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.
The Journal of physiology - 15 Jun 2007
Hadley Stephen H, Amin Jahanshah
Abstract excerpt
The onset of motor learning in rats coincides with exclusive expression of GABAA receptors containing alpha6 and delta subunits in the granule neurons of the cerebellum. This development temporally correlates with the presence of a spontaneously active chloride current through alpha6-containing GABAA receptors, known as tonic inhibition. Here we report that the coexpression of alpha6, beta2, and delta subunits...
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