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Article

Genetic manipulations of GABAA receptor in mice make inhibition exciting.

Pharmacology & therapeutics - 1 Aug 2004

Vicini Stefano, Ortinski Pavel

Abstract excerpt

The inhibitory neurotransmitter gamma-aminobutyric acid (GABA) plays an important role in brain development and behavior. GABA(A) receptor subunits knock-out and knock-in mice have proven that GABA(A) receptors are involved in control of motor coordination, learning, and memory and play a role in anxiety, panic, and epileptogenesis. In addition, these receptors are involved in the molecular mechanisms of action...

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Identifiers

PMID: 15369679
DOI: 10.1016/j.pharmthera.2004.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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