Article
Loreclezole and La3+ differentiate cerebellar granule cell GABA(A) receptor subtypes.
European journal of pharmacology - 12 Feb 1999
Mäkelä R, Wisden W, Korpi E R
Abstract excerpt
The effects of loreclezole and La3+ on native cerebellar GABA(A) receptors were compared between GABA(A) receptor alpha6 subunit-deficient (alpha6-/-) and wildtype mouse lines, produced through homologous recombination, using t-[35S]butylbicyclophosphorothionate ([35S]TBPS) autoradiography in brain sections. In the alpha6 subunit-deficient mice, the GABA receptor antagonistic ability of La3+ was abolished in the...
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