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Article

Evidence for rapid disappearance of initially expanded HIV-specific CD8 <sup>+</sup> T cell clones during primary HIV infection

2 Sept 1997

Abstract excerpt

Down-regulation of the initial burst of viremia during primary HIV infection is thought to be mediated predominantly by HIV-specific cytotoxic T lymphocytes, and the appearance of this response is associated with major perturbations of the T cell receptor repertoire. Changes in the T cell receptor repertoire of virus-specific cytotoxic T lymphocytes were analyzed in patients with primary infection to understand...

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PMID: 9275214
DOI: 10.1073/pnas.94.18.9848

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Evidence for rapid disappearance of initially expanded HIV-specific CD8 <sup>+</sup> T cell clones during primary HIV infectionPMID 9275214Read ↗

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