Article
Frequency and function of HIV-specific CD8(+) T cells.
Immunology letters - 1 Nov 2001
Migueles S A, Connors M
Abstract excerpt
The virus-specific CD8(+) T cell responses of 27 HIV-infected patients were studied, including a unique cohort of long term nonprogressors (LTNP) with normal CD4(+) T cell counts, low levels of plasma viral RNA, strong proliferative responses to HIV antigens and an over-representation of the HLA B*5701 class I allele. The frequencies of CD8(+) T cells specific to the majority of HIV gene products were measured by...
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