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Article

Role of CD8+ T Cells in the Selection of HIV-1 Immune Escape Mutations.

Viral immunology - 1 Jan 2000

Arcia David, Acevedo-Sáenz Liliana, Rugeles María Teresa, Velilla Paula A

Abstract excerpt

Human immunodeficiency virus type-1 (HIV-1) infection represents one of the biggest public health problems worldwide. The immune response, mainly the effector mechanisms mediated by CD8+ T cells, induces the selection of mutations that allows the virus to escape the immune control. These mutations are generally selected within CD8+ T cell epitopes restricted to human leukocyte antigen class I (HLA-I), leading to...

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Share to CD8-Positive T-Lymphocytes
Share to Epitopes, T-Lymphocyte
Share to Genetic Fitness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27805477
DOI: 10.1089/vim.2016.0095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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