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Article

Evolution of CD8+ T cell immunity and viral escape following acute HIV-1 infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2003

Cao Jianhong, McNevin John, Malhotra Uma, McElrath M Juliana

Abstract excerpt

Induction of HIV-1-specific CD8(+) T cells during acute infection is associated with a decline in viremia. The role CD8(+) effectors play in subsequently establishing viral set point remains unclear. To address this, we focused on two acutely infected patients with the same initial Tat-specific CD8(+) response, analyzing their CD8(+) T cell responses longitudinally in conjunction with viral load and sequence...

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Share to Acute Disease
Share to CD8-Positive T-Lymphocytes
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to Gene Products, tat

Share to Immunity, Cellular

Share to Interferon-gamma

Share to tat Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 14500685
DOI: 10.4049/jimmunol.171.7.3837

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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