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Article

Resistance to monoclonal antibody-induced CD8+ T-cell depletion in thymectomized MHC class II-deficient mice.

Transplantation - 15 Aug 1997

Zhao Y, Sykes M

Abstract excerpt

BACKGROUND: CD8+ T cells are present at higher than normal levels in MHC class II-deficient (IIKO) mice. METHODS: In this study, we have examined the sensitivity of CD8+ T cells to depletion induced by a single injection or multiple injections of an anti-CD8 monoclonal antibody (mAb) (2.43) in IIKO mice in vivo. RESULTS: Thymectomized (ATX) IIKO mice showed the presence of a greater percentage of memory CD8+ T...

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Identifiers

PMID: 9275117
DOI: 10.1097/00007890-199708150-00019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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