CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice.

doi:10.1084/jem.182.4.993

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Article

CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice.

The Journal of experimental medicine - 1 Oct 1995

Cardell S, Tangri S, Chan S, Kronenberg M, Benoist C, Mathis D

Abstract excerpt

Rather unexpectedly, major histocompatibility complex class II-deficient mice have a significant population of peripheral CD4+ T lymphocytes. We have investigated these cells at the population and clonal levels. CD4+ T lymphocytes from class II-deficient animals are thymically derived, appear early in ontogeny, exhibit the phenotype of resting memory cells, are potentially functional by several criteria, and have...

Topics

Animals
Antigens, CD1
Autoimmunity
Base Sequence
CD4-Positive T-Lymphocytes
Clone Cells
Genetic Variation
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Hybridomas
Lymph Nodes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred BALB C

Mice, Inbred C57BL

Mice, Inbred DBA

Mice, Inbred NOD

Molecular Sequence Data

Receptors, Antigen, T-Cell, alpha-beta

Source

Open in PubMed Open full text

Identifiers

PMID: 7561702
DOI: 10.1084/jem.182.4.993
PMCID: PMC2192275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7561702-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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