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Article

CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice.

The Journal of experimental medicine - 1 Oct 1995

Cardell S, Tangri S, Chan S, Kronenberg M, Benoist C, Mathis D

Abstract excerpt

Rather unexpectedly, major histocompatibility complex class II-deficient mice have a significant population of peripheral CD4+ T lymphocytes. We have investigated these cells at the population and clonal levels. CD4+ T lymphocytes from class II-deficient animals are thymically derived, appear early in ontogeny, exhibit the phenotype of resting memory cells, are potentially functional by several criteria, and have...

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Identifiers

PMID: 7561702
DOI: 10.1084/jem.182.4.993
PMCID: PMC2192275

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Source receipt: pubmed, retrieved 7 Sept 2026.

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