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Article

Role of MHC class II on memory B cells in post-germinal center B cell homeostasis and memory response.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2006

Shimoda Michiko, Li Tao, Pihkala Jeanene P S, Koni Pandelakis A

Abstract excerpt

We investigated the role of B cell Ag presentation in homeostasis of the memory B cell compartment in a mouse model where a conditional allele for the beta-chain of MHC class II (MHC-II) is deleted in the vast majority of all B cells by cd19 promoter-mediated expression of Cre recombinase (IA-B mice). Upon T cell-dependent immunization, a small number of MHC-II(+) B cells in IA-B mice dramatically expanded and...

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Source

Identifiers

PMID: 16455968
DOI: 10.4049/jimmunol.176.4.2122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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