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THYMIC DEPENDENCE OF LOSS OF TOLERANCE IN MIXED ALLOGENEIC BONE MARROW CHIMERAS AFTER DEPLETION OF DONOR ANTIGEN

1 Aug 1996

Abstract excerpt

A nonmyeloablative conditioning regimen has recently been developed that allows allogeneic marrow engraftment with induction of permanent mixed chimerism and donor-specific tolerance across fully MHC-mismatched allogeneic barriers. We recently demonstrated that tolerance can be broken in these chimeras by administration of an anti-donor class I-specific monoclonal antibody that eliminates donor hematopoietic...

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PMID: 8779687
DOI: 10.1097/00007890-199608150-00014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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