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Article

Effects of in vivo T lymphocyte subset depletion on mycobacterial infections in mice.

Journal of leukocyte biology - 1 Mar 1992

Flory C M, Hubbard R D, Collins F M

Abstract excerpt

The relative importance of CD4+ and CD8+ T cell subsets in the expression of acquired resistance to systemic infection by Mycobacterium kansasii was determined. T cell subsets were depleted in thymectomized C57BL/6 mice by the intravenous administration of monoclonal antibodies directed against the relevant T cell determinants. Depletion of the CD4+ subset exacerbated the severity of the infection in...

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Identifiers

PMID: 1347311
DOI: 10.1002/jlb.51.3.225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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