Article
Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis.
Cell - 12 Jul 1991
Chaillet J R, Vogt T F, Beier D R, Leder P
Abstract excerpt
Genomic imprinting is a regulatory process that requires a cell to recognize the parental origin of alleles. To understand how these alleles are distinguished, we have assessed changes in the DNA methylation of an imprinted transgene as it switches from one inheritance pattern to another while moving through gametogenesis and embryogenesis. We find that both maternally and paternally inherited methylation...
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