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Article

Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis.

Cell - 12 Jul 1991

Chaillet J R, Vogt T F, Beier D R, Leder P

Abstract excerpt

Genomic imprinting is a regulatory process that requires a cell to recognize the parental origin of alleles. To understand how these alleles are distinguished, we have assessed changes in the DNA methylation of an imprinted transgene as it switches from one inheritance pattern to another while mo...

Topics

Alleles
Animals
Avian Sarcoma Viruses
DNA
Embryo, Mammalian
Female
Gametogenesis
Genes, myc
Immunoglobulin Heavy Chains
Male
Methylation
Mice
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Oogenesis

Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 1649008
DOI: 10.1016/0092-8674(91)90140-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1649008-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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