Article
Genomic imprinting: lessons from mouse transgenes.
Mutation research - 1 Jun 1994
Chaillet J R
Abstract excerpt
Genomic imprinting is a non-Mendelian form of inheritance that results in an expression difference between the two parental alleles of an autosomal locus. The study of mouse transgenes has provided us with descriptions of a variety of imprinting or parent-of-origin effects, thereby anticipating similar inheritance phenomena in non-transgenic mice. Many mouse transgenes exhibit parent-of-origin behavior only on...
Topics
- Alleles
- Animals
- Blastocyst
- DNA
- Female
- Gametogenesis
- Gene Expression Regulation
- Genome
- Male
- Methylation
- Mice
- Mice, Transgenic
- Parents