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Article

Stabilising and destabilising modifications of cysteines in the E. coli outer membrane porin protein OmpC.

FEBS letters - 14 Jul 1997

Gokce I, Bainbridge G, Lakey J H

Abstract excerpt

Three sulfhydryl labels were used to modify two mutated sites, R37C and R74C in the eyelet of the outer membrane porin OmpC. Modification of R37C with the neutral groups Aldrithiol and bimane increases thermal stability but the negatively charged iodoacetate causes a decrease in thermal stability. The effects of substitution at R74C were less significant. Bimane labelling increases the voltage sensitivity and...

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Identifiers

PMID: 9271205
DOI: 10.1016/s0014-5793(97)00690-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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