Inhibitory effect of acidic pH on OmpC porin: wild-type and mutant studies.

doi:10.1016/s0014-5793(98)00975-2

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Article

Inhibitory effect of acidic pH on OmpC porin: wild-type and mutant studies.

FEBS letters - 28 Aug 1998

Liu N, Delcour A H

Abstract excerpt

By use of the patch clamp technique, we have compared the electrophysiological signature of OmpC porin channels at neutral and acidic pH. The perfusion of pH 5.4 buffer to the periplasmic side of excised patches promoted the closure or block of approximately 20% of the open porins present in the...

Topics

Electrophysiology
Escherichia coli
Hydrogen-Ion Concentration
Ion Channel Gating
Ion Channels
Mutation
Porins

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