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Article

The ionization state of D37 in E. coli porin OmpF and the nature of conductance fluctuations in D37 mutants.

European biophysics journal : EBJ - 1 Nov 2010

Vrouenraets Maarten, Miedema Henk

Abstract excerpt

Understanding the flow of ions through E. coli porin outer membrane protein F (OmpF) requires knowledge of the charge state of all titratable residues located along the permeation pathway. Earlier theoretical studies proved successful in the calculation of the pK values of most residues. The (apparent) pK of Asp37 (D37), on the other hand, appeared rather sensitive to the (unknown) protein dielectric used. We...

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Identifiers

PMID: 20521145
DOI: 10.1007/s00249-010-0613-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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