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Article

Cysteine Modification: Probing Channel Structure, Function and Conformational Change.

Advances in experimental medicine and biology - 1 Jan 2015

Akabas Myles H

Abstract excerpt

Cysteine substitution has been a powerful tool to investigate the structure and function of proteins. It has been particularly useful for studies of membrane proteins in their native environment, embedded in phospholipid membranes. Among the 20 amino acids, cysteine is uniquely reactive. This reactivity has motivated the synthesis of a wide array of sulfhydryl reactive chemicals. The commercially available array...

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PMID: 26381939
DOI: 10.1007/978-1-4939-2845-3_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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