Article
T helper 2-dominant antilymphoma immune response is associated with fatal outcome.
Blood - 15 Aug 1997
Lee P P, Zeng D, McCaulay A E, Chen Y F, Geiler C, Umetsu D T, Chao N J
Abstract excerpt
The precise role of the endogenous immune system in modulating cancer development remains unclear. Tumor cells are generally thought to be nonimmunogenic because they are of 'self' origin. However, tumor-reactive lymphocytes can be isolated from patients with many types of cancer. It is unclear what role these lymphocytes play and why they fail to protect the host. Using a murine B-cell leukemia/lymphoma (BCL1)...
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