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Distinct T helper cell-mediated antitumor immunity: T helper 2 cells in focus

4 Nov 2022

Abstract excerpt

) T cells, which mediate T helper (Th) 1 immunity (type 1 immunity), are the primary Th cell subtype associated with tumor elimination. In this review, we discuss evidence showing that antitumor immunity and better prognosis can be associated with distinct Th cell subtypes in experimental mouse models and humans, with a focus on Th2 cells. The aim of this review is to provide an overview and understanding of the...

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PMID: 38328613
DOI: 10.1016/j.cpt.2022.11.001

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