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Article

Rapid deletion and inactivation of CTLs upon recognition of a number of target cells over a critical threshold.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2013

Prato Sandro, Zhan Yifan, Mintern Justine D, Villadangos Jose A

Abstract excerpt

Initiation of CTL responses against foreign pathogens also primes anti-self CTLs. Mechanisms of CTL inactivation inhibit anti-self CTLs to prevent tissue damage. These mechanisms are exploited by pathogens and tumors to evade the immune response, and present a major hurdle to adoptive CTL therapi...

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Identifiers

PMID: 24018271
DOI: 10.4049/jimmunol.1300803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24018271-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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