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Article

CD8+CD44(hi) but not CD4+CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHD.

Blood - 17 Mar 2011

Dutt Suparna, Baker Jeanette, Kohrt Holbrook E, Kambham Neeraja, Sanyal Mrinmoy, Negrin Robert S, Strober Samuel

Abstract excerpt

Allogeneic hematopoietic cell transplantation can be curative in patients with leukemia and lymphoma. However, progressive growth of malignant cells, relapse after transplantation, and graft-versus-host disease (GVHD) remain important problems. The goal of the current murine study was to select a freshly isolated donor T-cell subset for infusion that separates antilymphoma activity from GVHD, and to determine...

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Identifiers

PMID: 21239702
DOI: 10.1182/blood-2010-10-312751
PMCID: PMC3062320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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