Article
Tumor dormancy and cell signaling. V. Regrowth of the BCL1 tumor after dormancy is established.
Blood - 15 Jun 1997
Vitetta E S, Tucker T F, Racila E, Huang Y W, Marches R, Lane N, Scheuermann R H, Street N E, Watanabe T, Uhr J W
Abstract excerpt
The majority of BALB/c mice immunized with the BCL1 lymphoma-derived idiotype (Id+) IgM and subsequently challenged with BCL1 tumor cells develop a state of tumor dormancy. The vast majority of dormant lymphoma cells are in cell cycle arrest, but there are also residual replicating cells. In the present studies, we attempted to define features of both the dormant lymphoma cells and the host that lead to escape...
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