Article
Cancer dormancy: isolation and characterization of dormant lymphoma cells.
Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1993
Yefenof E, Picker L J, Scheuermann R H, Tucker T F, Vitetta E S, Uhr J W
Abstract excerpt
"Tumor dormancy" is an operational term used to describe a prolonged quiescent state in which tumor cells are present, but tumor progression is not clinically apparent. Although clinical examples of tumor dormancy abound, little is known regarding the mechanisms underlying this state. Here we utilize an antibody-induced dormancy model of an aggressive murine B-cell lymphoma (BCL1) and show that the induction of...
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