Article
[Genetic polymorphism in sparteine oxidation--occurrence in healthy volunteers in Slovakia].
Bratislavske lekarske listy - 1 Feb 1997
Holomán J, Glasa J, Veningerová M, Prachar V, Lukácsová M
Abstract excerpt
The aim of this study was to estimate the occurrence of the phenotype of poor metabolizers of sparteine (in the frame of sparteine-debrisoquine-dextromethorphane polymorphism) in Slovakia. The authors examined a group of 216 of healthy volunteers (73 women and 143 men, average age of the group 24, 9 +/- 0.4 years), university students coming from various regions of Slovakia. The test substance-sparteine (1 x 100...
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